• DNA methylation is a relatively stable but reversible epigen

  2019-09-21

  

  DNA methylation is a relatively stable but reversible epigenetic mechanism that can regulate gene expression, and occurs at the three different cytosine sequence contexts (CG, CHG, and CHH, where H is C, A, or T) in plants [15]. Many studies suggest that DNA methylation status of genes influence pla

• Cyanine 5-dUTP kinase The enzyme cyclooxygenase COX or prost

  2019-09-21

  

  The enzyme cyclooxygenase (COX) or prostaglandin endoperoxide H synthase (PGHS) is the key enzyme in the conversion of arachidonic Cyanine 5-dUTP kinase (AA) into prostaglandins (PGs) [1]. In 1991, researchers found that there were two isoforms of this enzyme called COX-1 and COX-2 with independent

• One significant finding in this study was

  2019-09-21

  

  One significant finding in this study was the overexpression of a protein identified as LysM domain/BON superfamily protein [29], [30]. This protein was highly overexpressed in the meropenem-treated condition. InterProScan analysis revealed that the LysM domain/BON superfamily protein consisted of t

• Introduction Prolyl hydroxylation is a widely observed post

  2019-09-21

  

  Introduction Prolyl hydroxylation is a widely observed post translational modification in collagen, an abundant animal protein. The high content (~13% per chain of the triple helical structure) of 4-hydroxyproline (Hyp,O) in collagen, togather with the natural abundance of collagen has led to the e

• br Conclusions In a former study

  2019-09-21

  

  Conclusions In a former study we compared the modulating potential of halogenated 1H-benzimidazole derivatives towards CK2 catalytic subunits. Now we were interested if similar differences are also obtained using completely different substances. Some of these natural occurring compounds were alre

• Cilnidipine br Results and discussion br Conclusions We

  2019-09-21

  

  Results and discussion Conclusions We have developed a method to produce wildtype and mutant Ric-8A proteins from E. coli that can be phosphorylated at the regulatory protein kinase CK2 phosphosites to near homogeneity. The phosphorylation status and activity of the purified Ric-8A proteins wa

• It is common for plants that are

  2019-09-21

  

  It is common for plants that are deficient in P to invest in their roots in order to maximise P uptake from the soil. Here, plants grown in soil amended with OA had a higher root biomass:shoot carbenicillin kinase ratio compared with plants in the INORG-P treatment. Additionally, greater allocation

• Chk is dramatically induce by

  2019-09-21

  

  Chk is dramatically induce by the IL-4 family of cytokines and equally dramatically inhibited by IFN-γ, a regulation that appears to be specific for human monocytes. In primary human T cells, Chk is not normally present, but it can be induced by potent activators of T Agar pathway such as PHA or IL

• ET expression occurs in many carcinomas including

  2019-09-21

  

  ET-1 expression occurs in many carcinomas, including those arising in the kidney [38], prostate [7], ovary [5] endometrium [39], melanocyte [40], and central nervous system [41], [42], among others [43]. The endothelin axis expression in RCC appears to be dependent upon the tumor subtype [38]. In se

• A 77-01 kinase Additionally although the membrane localized

  2019-09-21

  

  Additionally, although the membrane-localized ER signaling described in this review has generally been studied in isolation from nuclear signaling, it is becoming clearer and clearer that integration of these mechanisms must be considered (Frick, 2015). Perhaps the distinct estradiol signaling mecha

• Enolase is an example of a moonlighting protein

  2019-09-21

  

  Enolase is an example of a moonlighting protein that displays multiple biological actions, including plasminogen, laminin, fibronectin, mucin and cytokeratin binding properties. It has also been described as a complement-evasion protein and as a protein capable of inducing neutrophil trap formation.

• br EBV Infection Epstein Barr virus

  2019-09-21

  

  EBV Infection Epstein–Barr virus (EBV, human herpesvirus 4) was discovered 50 years ago, when Epstein, Achong, and Barr used electron microscopy to identify viral particles in Burkitt\'s lymphoma cells. It belongs to the lymphocryptovirus (LCV) genus of the gammaherpesvirus subfamily (Fig. 1A). T

• br Experimental methods br Results and discussion br Conclus

  2019-09-21

  

  Experimental methods Results and discussion Conclusion Rational design of highly selective fluorescent probes to detect G-quadruplexes is of profound importance for basic research. On this basis, we designed and synthesized a series of N-alkylated styrylquinolinium dyes Ls-1, Ls-2 and Ls-3.

• Multiple sequence alignment of the proteins in the DGAT

  2019-09-21

  

  Multiple sequence alignment of the proteins in the DGAT1 sub-family shows that there are about 41 conserved amino Ro 48-8071 residues distributed over seven sequence motifs [74]. Unlike DGAT2, a large number of DGAT1 residues, including a majority of the conserved residues, are found in a loop on t

• br Results and Discussion br Conclusions

  2019-09-21

  

  Results and Discussion Conclusions Based on their common NTP pyrophosphatase activity, similar size of the catalytic domains, and the conservation of glutamate residues, it was assumed previously that the MazG and HisE families were related to MutT and other Nudix family hydrolases (see Zhang

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