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The effect of capital deductions on equilibrium
2024-03-15
The effect of capital deductions on equilibrium prices is given by the following comparative statics Thus, equilibrium prices are strictly decreasing in the share of capital cost deduction. The reason is that a higher share of capital cost deduction reduces the effective marginal costs, which makes
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Signaling through Axl can lead to activation of the
2024-03-15
Signaling through Axl can lead to activation of the PI3K/Akt and Ras/MAPK pathways which promote cellular phenotypes (e.g., transformation, migration) consistent with pro-survival and pro-metastatic effects., , Inhibition of Axl activity by a variety of approaches (including pharmacologic, dominant
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Saxagliptin synthesis The inhibition of ACLY induces an anti
2024-03-15
The inhibition of ACLY induces an anticancer effect that has been reported to be involved in mitochondrial reactive oxygen species (ROS) generation [14], [16], dual blockade of mitogen-activated protein kinase and phosphatidylinositol-3-kinase/AKT pathways [11], and the glycolytic phenotype of tumor
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br Acknowledgements br Introduction Double
2024-03-15
Acknowledgements Introduction Double-stranded DNA breaks (DSBs) are among the most deleterious DNA lesions that threaten genomic integrity. DSBs are generated not only by exogenous DNA-damaging agents but also by normal cellular processes such as V(D)J recombination, meiosis, and DNA replicati
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br Discussion br Acknowledgments Writing
2024-03-15
Discussion Acknowledgments Writing of this review and collection of data from our laboratories that are presented were supported by a grant from the Belgian Science Policy (BELSPO) SSTC Interuniversity Attraction Poles Plastoscine P7/17 to AVDL and JB, multiple grants from the Fund for Scienti
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In our previous report salivary arginase levels
2024-03-15
In our previous report, salivary arginase levels were found to be higher in periodontitis patients compared to healthy controls (Ozmeriç, Elgün, & Uraz, 2000). However, only one study has investigated arginase ezyme in saliva in patients with dental implants in which smokers were also included. An i
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br Introduction Endothelial progenitor cells EPCs present
2024-03-15
Introduction Endothelial progenitor cells (EPCs) present a class of blood cells with an ability to form new blood vessels relying on pre-existing vessels, which contribute to postnatal angiogenesis [1], [2]. A wide range of studies have demonstrated that EPCs play a critical role in angiogenesis
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PGC mediated mitochondrial biogenesis in
2024-03-14
PGC-1α-mediated mitochondrial biogenesis in brown fat and endothelial sgk inhibitor is in part regulated by eNOS and NO [28], [29]. Recent studies indicate that H2S not only augments NO bioavailability and signaling [11], [17], but provides protection against cardiac injury in an eNOS-dependent man
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Sodium 4-Aminosalicylate To elucidate this relationship we d
2024-03-14
To elucidate this relationship, we developed a spatial model of Ca-influx through N-methyl-D-aspartate receptor (NMDAR), CaMKII/PP1 activation, and AMPAR insertion in a realistic spine geometry. Using this model, we show that i) variables in membrane voltage mediated Ca-influx, particularly the num
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All desired compounds with a
2024-03-14
All desired compounds with a carboxylic Phosphoramidon Disodium Salt substituent at N1 position of the quinoxalinone scaffold and a variety of aromatic substituents at C3 position were obtained by the syntheses starting from methoxy-substituted 3-chloro-quinoxalin-2(1)-ones () prepared as previousl
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Endogenous adenosine systems have largely been implicated in
2024-03-14
Endogenous adenosine systems have largely been implicated in drug actions by the demonstration that caffeine (non-selective A1R and A2AR antagonist) (see Section The issue of caffeine), in doses up to 7.5–10mg/kg, inhibits antinociception, and when this occurs, it bet bromodomain is generally also
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Metformin s pluripotent roles are alluded to
2024-03-14
Metformin's pluripotent roles are alluded to in terms of its antitumorigenic, glucose-lowering, and cardioprotective effects, which are due in part to its upregulation of AMPK activity [39,40]. Metformin's glucose-lowering effect is a result of reduced hepatic gluconeogenesis, whereas improved insul
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Metaphit synthesis Actin is capable of polymerizing
2024-03-14
Actin is capable of polymerizing spontaneously. However, this process is relatively slow and kinetically unfavorable in cells. Formation of Metaphit synthesis dimers and trimers, which can easily disassemble due to their instability, is a rate-determining step in actin polymerization [5], [6]. The
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Whereas more research is needed to identify the
2024-03-14
Whereas more research is needed to identify the precise mechanism by which FIN exerts its antidyskinetic effect, the Pirfenidone that it can negatively modulate dopaminergic transmission is also supported by our previous findings. Indeed, we have previously shown that FIN completely reversed the be
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br Disclosure statement br Acknowledgements The work was
2024-03-14
Disclosure statement Acknowledgements The work was supported by the National Science Foundation of China (Nos. 81273526, 81473268) and Natural Science Foundation of Colleges and Universities (Nos. KJ2017A197). What is already known What this article adds Introduction Sevoflurane is o
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